Placenta Injection (Melsmon & Laennec)

Placenta injection (Melsmon or Laennec) for skin, fatigue, and menopause support.

十条駅ハル内科・皮膚科クリニック_プラセンタ注射

Placenta Injection Counseling

Melsmon® / Laennec® / Placenta-derived extract for beauty, menopause, and fatigue improvement treatments

What is Placenta Injection?

Placenta refers to the placenta. The placenta is rich in physiologically active substances such as growth factors, amino acids, nucleic acids, vitamins, and minerals necessary to support fetal development. Placenta injections are refined and formulated versions of these substances.

We offer two types of preparations at our clinic: Melsmon® and Laennec®. Both are human placenta-derived medical drugs with confirmed high safety.

Main Features of Placenta Injections

  • Diverse Effects: A wide range of effects can be expected, including alleviation of menopausal symptoms, fatigue recovery, skin beautification, liver function improvement, and immune regulation.
  • Covered by Insurance: Insurance coverage applies to the treatment of menopausal disorder in women aged 45-59 or for chronic liver disease.
  • High Safety: With a long history of use in Japan, it is a safe treatment with few side effects.
  • Enhanced Effects with Continued Use: Regular administration leads to cumulative effects.

Mechanism of Action

The physiologically active substances contained in placenta act on various tissues and organs of the body.

Effects of Placenta Injection Placenta-derived physiologically active substances act on various body tissues Placenta Extract Growth factors, amino acids, nucleic acids, vitamins Ovaries/Uterus Hormone balance adjustment Liver Cell regeneration/Detoxification promotion Skin/Hair Collagen production promotion Immune System Immune regulation Menopausal Symptom Improvement Hot flashes, malaise, insomnia Liver Function Improvement Chronic liver disease, fatigue recovery Skin Beautification/Anti-aging Firmness, radiance, spot improvement Fatigue Recovery Immune system boost The effects accumulate with regular administration. Start with 1-2 administrations per week, and adjust the frequency according to symptom improvement.

Recommended for those who:

  • Suffer from menopausal symptoms (hot flashes, flushing, malaise, insomnia, irritability)
  • Cannot get rid of chronic fatigue or want to recover from fatigue faster
  • Are concerned about skin firmness, radiance, and spots (skin beautification/anti-aging)
  • Are concerned about liver function values or have chronic liver disease
  • Want to boost their immune system and improve their overall health
  • Are concerned about hair strength and shine (hair growth/hair care effects)

Differences between the two preparations: Melsmon® vs Laennec®

Item Melsmon® Laennec®
Manufacturer Mochida Pharmaceutical Japan Bio Products
Main Target Improvement of menopausal symptoms Liver function improvement, beauty, fatigue recovery
Injection Method Subcutaneous or intramuscular injection possible Intramuscular injection (deeper injection)
Insurance Coverage Conditions Menopausal disorder (women aged 45-59) Chronic liver disease (for liver function improvement)
Beauty/Fatigue Recovery Purposes Self-pay treatment Self-pay treatment

About Insurance Coverage

Placenta injections are covered by health insurance under certain conditions. As it can significantly reduce costs compared to self-pay treatment, please inform eligible patients about insurance coverage.

Conditions for Insurance Coverage

Preparation Conditions for Insurance Coverage Target Age
Melsmon® For treatment of menopausal disorder (hot flashes, flushing, malaise, insomnia, etc.) Women aged 45-59
Laennec® For treatment of chronic liver disease (chronic hepatitis, liver cirrhosis, etc.) No age limit
※Insurance coverage requires a doctor's diagnosis. Insurance may not apply depending on symptoms or test results. ※For beauty or fatigue recovery purposes, even if conditions are met, treatment will be self-pay.

Estimated Cost for Insurance Coverage (30% self-pay)

Content Estimated Cost (tax included, 30% self-pay)
Re-examination fee Approximately ¥230
Melsmon injection (including procedure fee) Several hundred yen (varies by dosage and additions)
Laennec injection (including procedure fee) Several hundred yen (varies by dosage and additions)
※Insurance costs vary depending on the content of treatment, additions, and prescriptions. Please confirm with a doctor or reception at the time of your visit.

For those wishing to use insurance coverage (confirmation points during consultation)

  • Menopausal disorder (Melsmon insurance coverage): Are there symptoms such as hot flashes, flushing, sweating, insomnia, irritability, malaise, and is the patient a woman aged 45-59?
  • Chronic liver disease (Laennec insurance coverage): Has the patient been diagnosed with chronic hepatitis, liver cirrhosis, fatty liver, or are there abnormalities in liver function values (AST, ALT, γ-GTP, etc.)?
  • History of treatment at other clinics/current medication status
  • If necessary, blood tests (liver function, hormone tests) will be performed to confirm the basis for insurance coverage.

Fee Schedule

Melsmon® (Self-pay treatment)

Menu Price (tax included)
Melsmon 1A ¥1,000
Melsmon 2A ¥1,800
Melsmon 3A ¥2,700
Melsmon 4A ¥3,600

Laennec® (Self-pay treatment)

Menu Price (tax included)
Laennec 1A ¥800
Laennec 2A ¥1,500
Laennec 3A ¥2,200
Laennec 4A ¥3,000
※A first consultation fee applies only for first-time visitors; no consultation fee for subsequent visits. ※Insurance coverage applies for treatment of menopausal disorder in women aged 45-59, or for chronic liver disease. ※Prices are subject to change without notice. Please check the latest prices at the clinic or on our website.

Consultation Flow

For Self-Pay Treatment

  1. Visit / WEB reservation: Please visit us directly or make a WEB reservation. We also accommodate walk-ins.
  2. Doctor's examination/consultation: The doctor will assess your symptoms and treatment goals, and suggest whether Melsmon or Laennec is more appropriate.
  3. Injection: Once prescribed, the injection can be administered on the same day. The procedure takes only a few minutes.
  4. Regular visits: Start with 1-2 administrations per week, and adjust the frequency according to your symptoms and the effects. No consultation fee for the second visit and onwards.

For Insurance Coverage

  1. Visit / WEB reservation: Please visit us directly or make a WEB reservation. Bring your health insurance card.
  2. Doctor's examination/consultation: Your symptoms and medical history will be reviewed. Blood tests (liver function, hormone tests) will be performed if necessary.
  3. Insurance coverage confirmation/Injection: The doctor will determine the eligibility for insurance coverage. If eligible, the injection will begin on the same day or after test results are available.
  4. Regular visits: The frequency of visits will be adjusted based on symptoms and effects. A consultation fee applies for each visit under insurance coverage, but the cost will be significantly lower than self-pay.
※Insurance coverage is available only to those who meet the eligibility criteria as diagnosed by a doctor. ※It is not possible to combine insurance coverage and self-pay treatment on the same day.

Pre-prescription Confirmation Items and Contraindications

Items to always confirm during consultation

  • History of allergy or hypersensitivity to placenta preparations
  • Pregnancy, breastfeeding, or planning pregnancy
  • Current treatment for or history of malignant tumors (cancer)
  • Presence of autoimmune disease
  • Presence of severe liver or kidney dysfunction
  • Types of medications and supplements currently being taken
  • Presence of milk or dairy product allergies (for Laennec)

Absolute Contraindications (those who cannot undergo treatment)

  • Those with a history of hypersensitivity to components of placenta preparations
  • Pregnant individuals
  • Those currently undergoing treatment for malignant tumors (cancer) (due to potential for promoting tumor cell proliferation)

Cautionary Administration (those for whom a doctor's judgment is required)

  • Breastfeeding individuals (consult with a doctor regarding transfer of components)
  • Those with autoimmune diseases (potential for effects due to immune-regulating action)
  • Those with severe allergies (recommended to observe in the clinic for about 30 minutes after administration)
  • Those with severe liver or kidney dysfunction

Main Side Effects and Explanations for Patients

Placenta injections have been used for many years in Japan and are a safe treatment with few side effects. However, the following side effects may occur. Please explain these to patients beforehand.

Common Side Effects (temporary)

  • Redness, swelling, pain, bruising at the injection site (improves within a few days)
  • Temporary lethargy or drowsiness after injection (may occur as a healing crisis)
  • Slight fever (rarely occurs with the first administration)
  • Itching, hives (allergic reaction)

Serious Side Effects (rare)

  • Anaphylaxis (generalized hives, difficulty breathing, drop in blood pressure)

Key Explanations for Patients

You may feel drowsy or lethargic immediately after starting administration, but this is often a healing crisis and subsides within a few days. After the first administration, please wait in our clinic for about 15 minutes, and you may return home once we confirm no abnormalities.

Placenta Injections and Blood Donation

Individuals who have received human-derived placenta preparations (Melsmon, Laennec) will not be able to donate blood. Please confirm and explain this thoroughly before administration.

Symptoms Requiring Immediate Medical Attention

  • Generalized hives, facial swelling, difficulty breathing (possible anaphylaxis)
  • Severe pain, swelling, or fever at the injection site lasting for several days or more
  • Persistent severe lethargy or fever

Important Notes

Post-procedure Precautions

  • It is recommended to avoid strenuous exercise, alcohol, and saunas on the day of the procedure.
  • Avoid rubbing the injection site vigorously.
  • The実感 of effects varies by individual. Continued administration leads to cumulative effects, so a minimum of 1-2 months of continued use is recommended.

About Continuous Administration

  • For the first 1-2 months, administration 1-2 times a week is recommended.
  • Once symptoms stabilize, the frequency can be reduced to once every 2-4 weeks.
  • No consultation fee for second and subsequent visits.
※This document is for in-clinic counseling only. Unauthorized reproduction or distribution is prohibited.
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