What is Placenta Injection?
Placenta injection is a treatment where human placenta extract (placenta preparation) is injected subcutaneously or intramuscularly. Medical placenta preparations (Melsmon and Laennec) approved by the Ministry of Health, Labour and Welfare are covered by insurance for menopausal disorder, lactation insufficiency, and chronic liver disease, and have over 50 years of clinical experience.
As a self-pay treatment, it is used for a wide range of purposes such as beauty (skin beautification, whitening), fatigue recovery, immune modulation, anti-aging, and allergies.
Safety of Placenta Preparations
Placenta preparations used in Japan are subject to strict infection control measures, such as prohibiting blood donation and organ transplantation for recipients. However, as a theoretical risk, there is a regulation that states recipients of placenta injections cannot donate blood.

Main Effects of Placenta
| Effect | Description |
|---|---|
| Autonomic and Endocrine Regulation | Balances hormones, improves menopausal symptoms |
| Antioxidant Effect | Removes active oxygen, prevents cell aging |
| Anti-inflammatory Effect | Alleviates chronic inflammation |
| Immune Activation/Modulation | Balances immunity |
| Liver Function Improvement | Improves liver function in chronic liver disease |
| Improved Blood Circulation | Improves blood flow and metabolism |
| Promotes Collagen/Elastin Production | Skin firmness and elasticity |
| Inhibits Melanin Production | Whitening, spot prevention |
| Promotes Tissue Repair | Wound healing, fatigue recovery |
Recommended for
Medical Purposes (May be covered by insurance)
- Symptoms of menopausal disorder (hot flashes, sweating, palpitations, insomnia, etc.) for women aged 45-59
- Postpartum lactation insufficiency
- Individuals with chronic liver disease and reduced liver function
Beauty and Health Purposes (Self-pay)
- Those who want to maintain skin firmness, radiance, and translucency
- Concerned about spots, dullness, and dryness
- Experiencing chronic fatigue and malaise
- Persistent cold sensitivity and stiff shoulders
- Relief from menstrual pain and PMS
- Allergic predisposition (atopy, hay fever)
- Want to boost immunity
- Anti-aging measures
Placenta Preparations Handled at Our Clinic
| Preparation | Characteristics | Main Indications |
|---|---|---|
| Melsmon | Mainly subcutaneous injection, insurance coverage for menopausal syndrome | Menopausal disorder (ages 45-59) |
| Laennec | Intramuscular injection, insurance coverage for chronic liver disease | Chronic liver disease, self-pay beauty |
Treatment Flow
- Counseling/Consultation: Confirm purpose, medical history, and medications
- Injection Site Selection: Subcutaneous (shoulder) or intramuscular (buttocks)
- Injection: 1-2mL, approximately a few seconds to 1 minute
- Aftercare: 5-10 minutes of rest, check vital signs
Time Required
The consultation and injection will be completed in approximately 10 to 20 minutes. It is available even for busy individuals.
Recommended Administration Frequency
| Purpose | Initial | Maintenance |
|---|---|---|
| Menopausal disorder (insurance coverage) | 1-3 times/week (1 month) | 1-2 times/week |
| Fatigue recovery/Beauty (self-pay) | 1-2 times/week (1-2 months) | Once a week or once every two weeks |
| Chronic liver disease | 2-3 times/week | Doctor's discretion |
| Anti-aging purposes | Once a week (3 months) | Once every two weeks or 1-2 times/month |
Consistency is Key for Efficacy
Instead of expecting dramatic changes in 1-2 sessions, the idea is to improve your constitution over 2-3 months of continuous treatment. The timing of feeling the effects varies individually depending on constitution and purpose.
Side Effects and Risks
Common Mild Side Effects
- Pain, redness, swelling, or hardening at the injection site
- Bruising
- Mild fever or malaise (for several days after injection)
- Allergic reaction at the injection site
Rare Side Effects
- Anaphylaxis (extremely rare)
- Shock
Individuals Who Cannot Receive Treatment
Contraindications
- History of allergy to placenta preparations
- Hypersensitivity to components of the preparation
- Currently have an active infection
Caution with Administration
- During pregnancy or lactation
- Infants and young children
- Severe heart, kidney, or liver failure
- Skin condition at the injection site
Important Note: Blood Donation Restrictions
Individuals who have received placenta injections cannot donate blood.
Due to the nature of human placenta-derived preparations, from the perspective of avoiding theoretical infection risk, individuals who have received placenta injections cannot donate blood. While there have been no actual infection reports in over 50 years of use, this is a regulation to ensure safety. If you are considering donating blood in the future, please consider this before receiving treatment.
Combination with Other Beauty Infusions/Injections
Placenta injections are effective alone, but synergistic effects can be expected when combined with other treatments.
- High-dose Vitamin C infusion: Antioxidant, whitening, skin firmness
- Glutathione infusion (Shiratamatenki): Whitening, liver function
- Garlic (Allithiamine) injection: Fatigue recovery
- Hyaluronic acid injection/Botox: Combination for beauty purposes
Price Guide
* This is an estimated price for self-pay. You will be informed during your consultation.
| Menu | Price |
|---|---|
| Placenta injection 1A (self-pay) | 1,000-1,500 yen |
| Placenta injection 2A (self-pay) | 1,800-2,500 yen |
| Menopausal disorder (ages 45-59, with insurance) | Several hundred yen with 30% co-pay |
| Chronic liver disease (with insurance) | 30% co-pay |
Features of Our Clinic's Placenta Injections
- Uses Ministry of Health, Labour and Welfare approved Melsmon and Laennec
- Insurance coverage for menopausal disorder reduces financial burden
- Also covered by insurance for chronic liver disease
- Reasonable pricing for self-pay beauty treatments
- Emphasizes counseling, proposes frequency according to purpose
- Treatment administered with consideration for overall health due to co-located internal medicine
- Can be combined with other beauty infusions/injections
- No appointment needed / walk-ins welcome / open daily 9 AM - 9 PM / 1-minute walk from Jujo Station
At a frequency you can comfortably maintain
Placenta is a treatment that improves your constitution, and consistency is key. Start with a manageable frequency and adjust as you observe the effects. Please feel free to consult us with any questions.





