About High-Dose Vitamin C Infusion
High-dose vitamin C infusion is a treatment that directly replenishes vitamin C (ascorbic acid) into the body via IV drip, achieving blood concentrations unattainable through oral intake. While oral intake has a blood concentration limit (approximately 200μM), IV drips can achieve blood concentrations tens to a hundred times higher than oral intake, and are expected to have a wide range of effects.
It is used globally for beauty (skin whitening, improved skin texture), fatigue recovery, immune system enhancement, anti-aging, and as a complementary therapy for cancer treatment, and has been adopted by many medical institutions in Japan.
Difference from oral intake
Even with oral intake of 1g or more, intestinal absorption has an upper limit, and blood concentration plateaus. With an IV drip, the absorption pathway is bypassed, and vitamin C directly enters the bloodstream, allowing for tens to a hundred times higher concentrations than oral intake.
Main Effects of Vitamin C
| Effect | Description |
|---|---|
| Antioxidant effect | Removes active oxygen, prevents cellular aging |
| Promotes collagen synthesis | Maintains skin firmness and elasticity, promotes wound healing |
| Melanin suppression | Improves spots and dullness, brightens skin |
| Supports immune function | Enhances white blood cell function, protects against infection |
| Promotes iron absorption | Positive effect on anemia prevention |
| Stress tolerance | Involved in cortisol synthesis in the adrenal glands |
| Vascular endothelial protection | Maintains blood vessel elasticity |
| Antitumor effect | Ultra-high doses selectively generate hydrogen peroxide in cancer cells; under research as a complementary therapy |
Recommended for those who:
- Are concerned about skin whitening, spots, and dullness
- Feel a decrease in skin firmness and elasticity
- Experience chronic fatigue
- Catch colds easily or want to boost immunity
- Live a high-stress lifestyle
- Are smokers (smoking consumes large amounts of vitamin C)
- Are in the recovery phase after severe infection
- Want to take anti-aging measures
- Are considering complementary therapy for cancer treatment
- Want to promote wound healing after surgery
Our Administration Dose Plans
You can choose from multiple doses according to your goals, physical condition, and lifestyle.
| Dose | Main Purpose | Time Required |
|---|---|---|
| 12.5g | Beauty, general health maintenance, initial introduction | 30–40 minutes |
| 25g | Fatigue recovery, enhanced beauty | 40–50 minutes |
| 50g | Serious beauty, immune system enhancement | 60–75 minutes |
| 75g | Anti-aging, chronic fatigue | 75–90 minutes |
| 100g or more (ultra-high dose) | Complementary therapy for cancer treatment | 90–120 minutes |
Pre-screening is mandatory for ultra-high doses (25g or more)
When administering 25g or more, screening for G6PD (glucose-6-phosphate dehydrogenase) deficiency is required. If this enzyme is deficient, there is a risk of hemolytic anemia with ultra-high doses of vitamin C.
Treatment Flow
- Initial consultation/examination: Confirm goals, medical history, and medications
- Pre-screening: First time (especially if requesting 25g or more), check G6PD activity, kidney function, and anemia
- IV drip preparation: Secure intravenous access, replenish fluids and salts as a precaution
- IV drip administration: Relax in a reclining chair (30–120 minutes)
- After treatment: Drink water, light meals are fine, can resume normal activities
Timing of Effect Realization
| Purpose | Estimate until effect is felt | Recommended Frequency |
|---|---|---|
| Fatigue recovery/Lethargy | Day of treatment to next day | 1–2 times a week |
| Skin whitening/Dullness improvement | 2–4 weeks | 1 time a week for 4–6 weeks, then 1–2 times a month |
| Skin firmness/Radiance | 2–3 months | Continue 1–2 times a month |
| Immune system enhancement | Several weeks~ | 1–2 times a month |
| Cancer complementary therapy | Depends on treatment period | 2–3 times a week (professional judgment) |
Effects vary by individual
The degree to which effects are felt varies by individual depending on their constitution, lifestyle, and existing oxidative stress levels. Many people only start to feel effects after continued use, so we recommend continuing for a while rather than judging after just 1–2 sessions.
Side Effects and Risks
Common Side Effects (Mild)
- Discomfort at the injection site/vein pain (can be reduced by adjusting the infusion speed)
- Feeling of warmth in the mouth or face (temporary)
- Mild headache/dizziness (hypoglycemia, electrolyte changes)
- Thirst (addressed by drinking water after administration)
- Mild diarrhea/gastrointestinal symptoms
- Bladder irritation due to osmotic pressure (feeling of frequent urination)
Rare Side Effects to Note
- Hemolytic anemia: In individuals with G6PD deficiency (excluded by pre-screening)
- Kidney stones (caution for those with a history)
- Impact on kidney function at high doses (contraindicated for those with kidney failure)
- Anaphylaxis (very rare)
- Hypoglycemia (caution for diabetics)
Who Cannot Receive Treatment
Contraindications
- G6PD deficiency
- Severe renal dysfunction (on dialysis, end-stage renal failure)
- Heart failure requiring salt and fluid restriction
- Elderly individuals with significantly weakened physical strength
- History of drug allergies
Cautionary Administration
- Pregnant or breastfeeding (consult with your primary doctor regarding suitability)
- Diabetes (blood glucose monitoring required)
- History of kidney stones
- Individuals taking medication (caution when used with some anticancer drugs)
Estimated Fees
* Self-pay medical treatment; varies depending on the area and number of units. Details will be provided during your consultation.
| Menu | Estimated Fee |
|---|---|
| Vitamin C Infusion 12.5g | 7,000〜10,000 yen |
| Vitamin C Infusion 25g | 12,000〜15,000 yen |
| Vitamin C Infusion 50g | 20,000〜25,000 yen |
| Vitamin C Infusion 75g | 28,000〜35,000 yen |
| G6PD Test (first time) | 3,000〜5,000 yen |
Combination with Other IV Drip Menus
Vitamin C infusion can be combined with other beauty and health IV drips for synergistic effects.
- Glutathione Infusion: Powerful antioxidant effect, skin whitening, liver function support
- Shiratamagic Infusion: Primarily glutathione, skin whitening, fatigue recovery
- Garlic (Alinamin) Injection: Fatigue recovery
- Placenta Injection: Female hormones, autonomic nervous system, beautiful skin
- Hydrogen Infusion: Antioxidant support
Precautions Before and After Treatment
Before Treatment
- Eat and hydrate sufficiently (fasting increases risk of hypoglycemia)
- Postpone if you have a fever or feel unwell
- G6PD test results are required for the first time (if requesting 25g or more)
- Disclose any medications you are taking in advance
After Treatment
- Drink plenty of water (1L or more)
- Avoid strenuous exercise
- You can resume normal activities the following day
- Contact us if you experience any concerning symptoms
Features of Our High-Dose Vitamin C Infusion
- Supports multiple doses from 12.5g to 100g depending on the objective
- G6PD testing is performed in advance for doses of 25g or more to ensure safety
- Treatment is performed after a comprehensive evaluation of physical condition and medical history, as the clinic has internal medicine
- Combinations with glutathione, Shiratamagic infusion, placenta, etc. are also possible
- Relaxed environment in reclining chairs
Balance of effectiveness and safety is crucial
High-dose vitamin C infusion is a safe treatment when performed appropriately. It is important to thoroughly conduct pre-screening and manage your physical condition, and continue with a dose and frequency that suits each individual. Please feel free to contact us if you have any questions.
Clinic Hours and Access
| Item | Content |
|---|---|
| Clinic Name | Jujo Station Haru Internal Medicine & Dermatology Clinic |
| Clinic Hours | Monday to Sunday, open daily from 9 AM. Wednesdays until 8 PM, Fridays and Saturdays until 9 PM, and Sundays until 7 PM. |
| Closed | None (irregular holidays) |
| Location | J&MALL 1F, 2-27-1 Kami-Jujo, Kita-ku, Tokyo 114-0034 |
| By Train/On Foot | Approx. 1-2 minute walk from JR Saikyo Line "Jujo Station," J&MALL 1F |
| By Bus | Immediately in front of the Kokusai Kogyo Bus "Jujo Station" bus stop |
| By Car | Please use nearby coin parking lots |
| Contact Us | TEL: 03-6698-2509 / Official LINE:https://lin.ee/AL0fp3z |





